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Doctors can prescribe spironolactone to treat a variety of different conditions, including heart failure, high blood pressure (hypertension) or low potassium levels in the blood (hypokalemia).


Spironolactone can also be used to treat fluid retention (edema) in patients with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. Reducing fluid retention can help to improve disabling symptoms, such as problems with breathing. You may also be prescribed spironolactone to treat low potassium levels or excessive aldosterone levels (hyperaldosteronism). 

To save the hassle of doctor’s appointments and waiting rooms, you can consult with a physician licensed in your state via our Seven Cells platform, to determine whether spironolactone could be the right treatment for you.

What is Spironolactone?

Spironolactone is a potassium-sparing diuretic - but you are more likely to have heard it being referred to as a “water pill”. Spironolactone belongs to a group of drugs, referred to as “aldosterone antagonists” and works by blocking the action of aldosterone, a hormone produced by the adrenal glands to help regulate the salt and water balance in your body. This prevents your body from absorbing too much salt and removes excess fluid from your body.

While most other diuretics cause a drop in the blood levels of potassium, spironolactone actually prevents your potassium levels from falling too low. This is why it is called a “potassium-sparing diuretic”.

Order Spironolactone online

Staying at home is now more important than ever. The Seven Cells platform offers a convenient and efficient way of accessing spironolactone directly from your phone, tablet, or computer. We will match you up with a licensed doctor in your state, who will talk through your symptoms and possible treatments with you via an online consultation. If appropriate, he or she will prescribe spironolactone for you and arrange for the medication to be delivered directly to your door. You won’t have to step foot inside a doctor’s office!

How to use

Once prescribed spironolactone, you must follow your doctor's directions carefully. Your allocated doctor will determine the correct dosage and frequency of medication for you. Remember to ask them if you have any questions. 

Spironolactone is available in a liquid or pill form and is taken orally. If you experience a stomach upset after taking the medication, you should try taking it with food or milk. Taking spironolactone early in the day (before 6 p.m.) will help to prevent nighttime urination from disrupting your sleep.

Spironolactone should be taken at the same time(s) every day, as directed by your doctor. If you have been prescribed spironolactone for high blood pressure, you should continue taking your medication even if you feel well. High blood pressure often causes no symptoms and your condition may worsen if you suddenly stop the drug.

Stay safe

Make sure that you read through all of the appropriate safety information before starting your medication. If you have any concerns or questions, then use the Seven Cells platform to discuss these with your doctor. Be sure to let your doctor know about any other medical conditions that you are suffering from as these may affect the use of this medicine.

Tell any other doctor or dentist that is treating you that you are taking spironolactone. Avoid using potassium supplements or salt substitutes containing potassium without consulting your doctor first, as spironolactone may increase your potassium levels. You should also limit your intake of foods which are high in potassium, such as bananas, tomatoes, potatoes and low-salt milk. It is advisable to limit alcoholic beverages while taking spironolactone.

As spironolactone may make you feel dizzy or drowsy, do not drive or operate heavy machinery until you are confident that you can perform these activities safely.

Side effects

Common side effects that can occur with spironolactone include drowsiness, lightheadedness, stomach upset, nausea, vomiting, diarrhea and headache. You can help to minimize lightheadedness by getting up more slowly when rising from a lying or seated position. As always, if you have any concerns or experience any lingering side effects, notify our medical professionals and we will be able to advise you accordingly. 

If you experience any of the following, rare but serious side effects, then you should seek medical advice immediately: dizziness, change in the amount of urine, increased thirst, mental/mood changes, muscle spasms, unusual fatigue/weakness, breast enlargement (gynecomastia) in men, sexual function problems, slow or irregular heartbeat, muscle weakness, signs of infection, severe abdominal pain, persistent nausea/vomiting, vomit that looks like coffee grounds, dark urine or yellowing of the eyes/skin.

While unlikely, seek emergency medical assistance if you experience any symptoms of an allergic reaction while taking spironolactone, including skin rashes, hives, trouble breathing, trouble swallowing and swelling of the face or limbs. 

Conditions where Spironolactone can help in varying doses:

Is Spironolactone for you?

From heart health to acne, your chances of being prescribed with Spironolactone are high due to the medicine’s many uses in treating different conditions in varying doses. 

How does Spironolactone work for so many conditions?

Spironolactone falls under a class of medicines called aldosterone receptor blockers or water pills. This causes the kidneys to eliminate excess water and sodium from the body but retain potassium in the body. What this means is, it helps in lowering blood pressure and preventing damage to the brain, heart, kidneys and other parts of the body.

Not only this, it helps in the treatment of acne, hirsutism and female hair loss due to its ability to block the production and action of male hormones in women. 

Conditions where Spironolactone can help in varying doses:

High blood pressure

Studies have shown that Spironolactone is effective in reducing blood pressure.

Heart health

Spironolactone has helped patients with acute heart failure, lowering the risk of hospitalization and increasing their chances of survival.

For edema

Spironolactone may help in relieving swelling in lower extremities.

Female pattern hair loss

44% of women on Spironolactone showed hair regrowth in a 2005 British Journal of Dermatology study.

For acne

Several studies have shown that Spironolactone improves acne in women. In one study for instance 85 women were treated with Spironolactone, of which, a third of the patients showed complete clearance of acne, another third had distinct improvement, and 27% had partial improvement. The majority of patients didn’t report any adverse effects associated with spironolactone treatment.

For excess hair growth

Studies have shown the effectiveness of Spironolactone in treating excess hair growth because it blocks androgen receptors and also decreases testosterone production, making it doubly effective for hirsutism.


As each condition requires different dosage of Spironolactone, your doctor will prescribe the recommended dose for your individual needs.  

What if I forget a dose?

If you missed a dose, resume as usual the next day. Don’t take two doses to make up for a missed one.

Side effects?

Like with other medications, Spironolactone is associated with side effects. If you plan to take Spironolactone, it’s important to understand what side effects you could expect. Seek medical help if you experience an allergic reaction to spironolactone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. 

It is important to call your doctor at once if you have little to no urination, hyperkalemia, symptoms of electrolyte imbalance like vomiting, confusion, slurred speech, numbness, weakness, confusion or feel light-headed, .

If you’re pregnant or planning to become pregnant let the doctor know before starting treatment.

Consult your doctor if you are concerned about side effects before beginning treatment and during treatment. Read the package insert that comes with the medicine for a full list of side effects and warnings.

The final word

Spironolactone ticks a lot of boxes and has helped a number of people with different conditions. But it will take time to achieve the results you desire. When it comes to blood pressure remember that Spironolactone will not cure it but will help in controlling it. And it’s a long term commitment, if treatment is not followed, high blood pressure can lead to serious problems related to your heart, blood vessels and kidney.

It is also important to remember that in addition to taking the medication, it is necessary to make changes in your lifestyle to help control your blood pressure. These changes include maintaining a healthy weight, eating a healthy diet low in fat and salt, exercising for at least 30 minutes several days a week, not smoking and drinking alcohol in moderation.